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Proceedings Paper

Optical fibers for improved light delivery in photodynamic therapy and diagnosis
Author(s): Bolesh J. Skutnik; Wolfgang Neuberger; Stefan Spaniol
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Paper Abstract

For most Photodynamic Therapy (PDT) applications a diffuse, broad and uniform source of irradiation is needed to obtain the most effective and consistent treatment. Since many treatments are within the patient's body, an effective compact fiber optic delivery system is needed for the activation of the photsensitizer drub at the site of the tissue to be treated. High Numerical Aperture (NA) optical fibers have benefits for PDT treatments but possibly even more so for PDT diagnostic applications These are summarized and new optical fibers with high and ultra high NAs are described. Properties of these fibers are presented as well as advantages they have over other fibers for delivering light in various PDT applications. Silica fibers with enhanced effective NAs approaching 0.6 are described.

Paper Details

Date Published: 14 June 2004
PDF: 6 pages
Proc. SPIE 5315, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XIII, (14 June 2004); doi: 10.1117/12.529489
Show Author Affiliations
Bolesh J. Skutnik, CeramOptec Industries, Inc. (United States)
Wolfgang Neuberger, Biolitec, Inc. (United States)
Biolitec AG (Germany)
Stefan Spaniol, Biolitec AG (Germany)


Published in SPIE Proceedings Vol. 5315:
Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XIII
David Kessel, Editor(s)

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