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Proceedings Paper

Oxygen saturation dependent absorption and scattering of whole blood
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Paper Abstract

We report on the scattering properties of oxygenated and de-oxygenated whole blood from 250-1000 nm. We determined the complex refractive index of oxygenated and de-oxygenated hemoglobin using Kramers Kronig analysis and Optical Coherence Tomography measurements. Combining these data with Mie theory, the scattering properties of oxygenated and deoxygenated whole blood were calculated. The results show strong oxygen saturation dependent scattering effects, which should be taken into account in data analysis of optical oxymetry.

Paper Details

Date Published: 1 July 2004
PDF: 7 pages
Proc. SPIE 5316, Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine VIII, (1 July 2004); doi: 10.1117/12.529057
Show Author Affiliations
Dirk J. Faber, Academic Medical Ctr., Univ. of Amsterdam (Netherlands)
Maurice C. G. Aalders, Academic Medical Ctr., Univ. of Amsterdam (Netherlands)
Egbert G. Mik, Academic Medical Ctr., Univ. of Amsterdam (Netherlands)
Brett A. Hooper, Duke Univ. (United States)
Ton G. van Leeuwen, Academic Medical Ctr., Univ. of Amsterdam (Netherlands)
Univ. Twente (Netherlands)


Published in SPIE Proceedings Vol. 5316:
Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine VIII
Valery V. Tuchin; Joseph A. Izatt; James G. Fujimoto, Editor(s)

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