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Proceedings Paper

Pulsed-ultrasound tagging of light in living tissues
Author(s): Aner Lev; E. Rubanov; Ami Pomerantz; Bruno Gad Sfez
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Paper Abstract

Ultrasound can be used in order to locally modulate, or tag, light in a turbid medium. This tagging process is made possible due to the extreme sensitivity of laser speckle distribution to minute changes within the medium. This hybrid technique presents several advantages compared to all-optical tomographic techniques, in that the image resolution is fixed by the ultrasound focus diameter. To our best knowledge, only in vitro experiments have been performed, either on tissue-like phantoms or meat. However a strong difference exists between these sample and living tissues. In living tissues, different kind of liquids flow through the capillaries, strongly reducing the sspeckle autocorrelation time. We have performed experiments on both mice and humans, showing that the autocorrelation time is much shorter than what was previously thought. We show however that it is possible to obtain signal with acceptable signal to noise ratio down to a few cm depth. We will also discuss the origin and characteristics of the speckle noise.

Paper Details

Date Published: 12 July 2004
PDF: 6 pages
Proc. SPIE 5320, Photons Plus Ultrasound: Imaging and Sensing, (12 July 2004); doi: 10.1117/12.524985
Show Author Affiliations
Aner Lev, Soreq Nuclear Research Ctr. (Israel)
E. Rubanov, Soreq Nuclear Research Ctr. (Israel)
Ami Pomerantz, Soreq Nuclear Research Ctr. (Israel)
Bruno Gad Sfez, Soreq Nuclear Research Ctr. (Israel)

Published in SPIE Proceedings Vol. 5320:
Photons Plus Ultrasound: Imaging and Sensing
Alexander A. Oraevsky; Lihong V. Wang, Editor(s)

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