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Proceedings Paper

Culture-based biochip for environmental monitoring
Author(s): Gaoshan Jing; Daniel B. Oerther; Ian Papautsky
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Paper Abstract

In this paper, we describe the development of a culture-based biochip for detecting mycobacteria in environmental samples. The biochips use the paraffinophilic nature of mycobacteria to rapidly detect and differentiate them from non-target micro-organisms. New methods of depositing and patterning paraffin were developed to fabricate prototype biochips. Biochips were experimentally tested to demonstrate rapid detection of mycobacteria in environmental samples collected from a municipal sewage treatment plant. Our successful demonstration of the culture-based biochip technology presents an alternative approach for developing new technology to track microorganisms in complex environmental samples.

Paper Details

Date Published: 23 December 2003
PDF: 10 pages
Proc. SPIE 5345, Microfluidics, BioMEMS, and Medical Microsystems II, (23 December 2003); doi: 10.1117/12.524610
Show Author Affiliations
Gaoshan Jing, Univ. of Cincinnati (United States)
Daniel B. Oerther, Univ. of Cincinnati (United States)
Ian Papautsky, Univ. of Cincinnati (United States)


Published in SPIE Proceedings Vol. 5345:
Microfluidics, BioMEMS, and Medical Microsystems II
Peter Woias; Ian Papautsky, Editor(s)

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