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Proceedings Paper

Linear and nonlinear reconstruction for diffuse optical tomography in an inhomogeneous background
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Paper Abstract

Diffuse Optical Tomography is a novel approach to imaging the body's optical properties non-invasively using non-ionizing electromagnetic radiation in the visible and near-infrared range. As spectral information at a number of measurement wavelengths can give important information about functional properties of tissue relatively deep withing the body, it is hoped that Optical Tomography will be clinically useful, particularly for detecting breast tumors and distinguishing between tumors and benign lesions. This paper formulates the fully three-dimensional linear and nonlinear inverse problems for Diffuse Optical Tomography and compares the linear and nonlinear reconstructions in a heterogeneous medium for a number of cases. In the first case, the background has a randomly varying lowpass structure. In the second case, the background has a layered structure with a sharp transition between layers, and, in the third case, the structure of the background is known, but not the corresponding optical properties.

Paper Details

Date Published: 21 May 2004
PDF: 12 pages
Proc. SPIE 5299, Computational Imaging II, (21 May 2004); doi: 10.1117/12.522927
Show Author Affiliations
Gregory Boverman, Northeastern Univ. (United States)
Eric L. Miller, Northeastern Univ. (United States)
David A. Boas, Massachusetts General Hospital (United States)


Published in SPIE Proceedings Vol. 5299:
Computational Imaging II
Charles A. Bouman; Eric L. Miller, Editor(s)

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