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Proceedings Paper

Separation of blood in microchannel bends
Author(s): Christoph Blattert; Reinhold Jurischka; Andreas Schoth; Paul Kerth; Wolfgang Menz
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Paper Abstract

Biological applications of micro assay devices require integrated on-chip microfluidics for separation of plasma or serum from blood. This is achieved by a new blood separation technique based on a microchannel bend structure developed within the collaborative Micro-Tele-BioChip (μTBC) project co-funded by the German Ministry For Education and Research (BMBF). Different prototype polymer chips have been manufactured with an UV-LIGA process and hot embossing technology. The separation efficiency of these chips has been determined by experimental measurements using human whole blood. Results show different separation efficiencies for cells and plasma depending on microchannel geometry and blood sample characteristics and suggest an alternative blood separation method as compared to existing micro separation technologies.

Paper Details

Date Published: 23 December 2003
PDF: 9 pages
Proc. SPIE 5345, Microfluidics, BioMEMS, and Medical Microsystems II, (23 December 2003); doi: 10.1117/12.522780
Show Author Affiliations
Christoph Blattert, Univ. Freiburg (Germany)
Reinhold Jurischka, Univ. Freiburg (Germany)
Andreas Schoth, Univ. Freiburg (Germany)
Paul Kerth, Preventor mikroTBC GmbH (Germany)
Wolfgang Menz, Univ. Freiburg (Germany)

Published in SPIE Proceedings Vol. 5345:
Microfluidics, BioMEMS, and Medical Microsystems II
Peter Woias; Ian Papautsky, Editor(s)

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