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Proceedings Paper

A fiber-optic-based biosensor to monitor mutans streptococci in saliva
Author(s): Anil Kishen; M. S. John; Chu Sing Lim; Anand Asundi
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Paper Abstract

A fiber optic biosensor to monitor mutans streptococci activity in human saliva is discussed. The developed biosensor is based on the selective bacterial growth medium and evanescent wave spectroscopy at the core-cladding interface of a multimode fiber to monitor the bacterial mediated biochemical reaction. In order to achieve this, a short length of the cladding is removed; the fiber core surface is treated and coated with a thin film of porous glass medium using sol-gel technique. During experiments, the mutans streptococci mediated reaction with sucrose is monitored using a photosensitive indicator, which is immobilized within the porous glass coating. This investigation highlights the potential benefits of the FOBS to monitor mutans streptococci activity in saliva.

Paper Details

Date Published: 13 October 2003
PDF: 8 pages
Proc. SPIE 5068, Saratov Fall Meeting 2002: Optical Technologies in Biophysics and Medicine IV, (13 October 2003); doi: 10.1117/12.518766
Show Author Affiliations
Anil Kishen, Nanyang Technological Univ. (Singapore)
M. S. John, Nanyang Technological Univ. (Singapore)
Chu Sing Lim, Nanyang Technological Univ. (Singapore)
Anand Asundi, Nanyang Technological Univ. (Singapore)


Published in SPIE Proceedings Vol. 5068:
Saratov Fall Meeting 2002: Optical Technologies in Biophysics and Medicine IV
Valery V. Tuchin, Editor(s)

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