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Proceedings Paper

Optical clearing of blood by dextrans
Author(s): Xiangqun Xu; Liu Wu; Ruikang K. Wang; James B. Elder; Valery V. Tuchin
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Paper Abstract

Effect of dextrans on optical property of blood in stasis and in flow was investigated with optical coherence tomography. The mechanisms for blood optical clearing are the characteristics of the types of dextrans employed and their concentrations. Among the substances applied, Dx500 at 0.5 gdl-1 and 5 gdl-1 are most effective in improving light penetration depth through the blood in stasis and in flow respectively. Optical clearing of blood was achieved by refractive index matching and aggregation of erythrocytes induced by dextrans.

Paper Details

Date Published: 22 September 2003
PDF: 8 pages
Proc. SPIE 5149, Laser Applications in Medicine, Biology, and Environmental Science, (22 September 2003); doi: 10.1117/12.518630
Show Author Affiliations
Xiangqun Xu, Cranfield Univ. (United Kingdom)
Liu Wu, Cranfield Univ. (United Kingdom)
Ruikang K. Wang, Cranfield Univ. (United Kingdom)
James B. Elder, Keele Univ. (United Kingdom)
Valery V. Tuchin, Saratov State Univ. (Russia)


Published in SPIE Proceedings Vol. 5149:
Laser Applications in Medicine, Biology, and Environmental Science
Gerhard Mueller; Valery V. Tuchin; Gennadii G. Matvienko; Christian Werner; Vladislav Ya. Panchenko, Editor(s)

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