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Proceedings Paper

Application of in vivo laser scanning microscope in dermatology
Author(s): Juergen Lademann; H. Richter; N. Otberg; F. Lawrenz; U. Blume-Peytavi; W. Sterry
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Paper Abstract

The state of the art of in-vivo and in-vitro penetration measurements of topically applied substances is described. Only optical techniques represent online measuring methods based on the absorption or scattering properties of the topically applied substances. Laser scanning microscopy (LSM) has become a promising method for investigations in dermatology and skin physiology, after it was possible to analyze the skin surface on any body side in-vivo. In the present paper the application of a dermatological laser scanning microscope for penetration and distribution measurements of topically applied substances is described. The intercellular and follicular penetration pathways were studied.

Paper Details

Date Published: 13 October 2003
PDF: 9 pages
Proc. SPIE 5068, Saratov Fall Meeting 2002: Optical Technologies in Biophysics and Medicine IV, (13 October 2003); doi: 10.1117/12.518622
Show Author Affiliations
Juergen Lademann, Charite (Germany)
H. Richter, Charite (Germany)
N. Otberg, Charite (Germany)
F. Lawrenz, Medizinelektronik Lawrenz GmbH (Germany)
U. Blume-Peytavi, Charite (Germany)
W. Sterry, Charite (Germany)


Published in SPIE Proceedings Vol. 5068:
Saratov Fall Meeting 2002: Optical Technologies in Biophysics and Medicine IV
Valery V. Tuchin, Editor(s)

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