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Proceedings Paper

Benzene degradation pathways investigated by a human-tissue-based biosensor
Author(s): Luigi Campanella; Patrizia Ercole; Rosella Grossi; Mario Vincenzo Russo; Giovanni Visco
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Paper Abstract

Benzene is determined by a biosensor based on human kidney tissue as biological component. Dioxygenase catalyse substrate oxidation. The useful analytical range results to be complementary to that of one or more traditional models based on Pseudomonas. The biosensors has got an other aim as its functioning is able to clear up the degradation pathways of benzene. The behavior of a biosensor based on cancerous human kidney tissue compared to healthy one let to hypothize a poor activity of dioxygenase in cancerous kidney, possibly to be tested with prevention strategy.

Paper Details

Date Published: 15 March 2004
PDF: 5 pages
Proc. SPIE 5261, Smart Medical and Biomedical Sensor Technology, (15 March 2004); doi: 10.1117/12.515600
Show Author Affiliations
Luigi Campanella, Univ. degli Studi di Roma La Sapienza (Italy)
Patrizia Ercole, Univ. degli Studi di Roma La Sapienza (Italy)
Rosella Grossi, Univ. degli Studi di Roma La Sapienza (Italy)
Mario Vincenzo Russo, Univ. degli Studi di Roma La Sapienza (Italy)
Giovanni Visco, Univ. degli Studi di Roma La Sapienza (Italy)


Published in SPIE Proceedings Vol. 5261:
Smart Medical and Biomedical Sensor Technology
Brian M. Cullum, Editor(s)

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