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Proceedings Paper

Optical local and superficial probing of tissues for in vivo diagnosis
Author(s): Philippe Thueler; Michel St. Ghislain; Christian D. Depeursinge; Igor Charvet; Paolo Meda; Ben Vermeulen
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Paper Abstract

An optical tissue diagnosis technique, often called "optical biopsy", has been developed, It is based on the simultaneous determination of the optical properties of tissues such as the reduced scattering coefficient μs’ and the absorption coefficient μa. These data are obtained by applying a small diameter probe (ψ 2mm) on tissues, through the working channel of usual endoscopes. The simultaneous determination of μa and μs’ with a local probe was made possible by the consideration of the first two moments of the phase function and a proven model of light propagation in tissues at propagation length comparable to the scattering mean free path. Non-invasive measurements of the optical coefficients of superficial tissues have been obtained in vivo (stomach) at different wavelength.

Paper Details

Date Published: 8 October 2003
PDF: 6 pages
Proc. SPIE 5141, Diagnostic Optical Spectroscopy in Biomedicine II, (8 October 2003); doi: 10.1117/12.500831
Show Author Affiliations
Philippe Thueler, Swiss Federal Institute of Technology, Lausanne (Switzerland)
Michel St. Ghislain, Swiss Federal Institute of Technology, Lausanne (Switzerland)
Christian D. Depeursinge, Swiss Federal Institute of Technology, Lausanne (Switzerland)
Igor Charvet, Univ. de Geneve (Switzerland)
Paolo Meda, Univ. de Geneve (Switzerland)
Ben Vermeulen, Univ. de Geneve (Switzerland)


Published in SPIE Proceedings Vol. 5141:
Diagnostic Optical Spectroscopy in Biomedicine II
Georges A. Wagnieres, Editor(s)

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