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Proceedings Paper

New method for confocal microscopy and its endoscopic application
Author(s): Ingo Krohne; Tilo Pfeifer; Frank Bitte; Michael Zacher; Richard Meier
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Paper Abstract

Today, confocal microscopy is widely used in biomedical applications, since its technology allows e.g. in cell biology to resolve sub- and intercelluar details in three-dimensions. Moreover, the recent miniaturization process of opto-electronical components even indicates a possible endoscopic application - to intraoperative examinations without need for a surgical biopsy. The current development of such a confocal endomicroscope, based on the concept of miniaturized fiberoptical components is described. The technical setup is explained in the context of an alternative method for confocal microscopy employing a Digital Micromirror Device (DMD). Moreover, in-vivo tissue staining techniques suitable for confocal endoscopic imaging are analyzed.

Paper Details

Date Published: 14 October 2003
PDF: 8 pages
Proc. SPIE 5143, Novel Optical Instrumentation for Biomedical Applications, (14 October 2003); doi: 10.1117/12.500763
Show Author Affiliations
Ingo Krohne, Fraunhofer Institute of Production Technology (Germany)
Tilo Pfeifer, Fraunhofer Institute of Production Technology (Germany)
Frank Bitte, Fraunhofer Institute of Production Technology (Germany)
Michael Zacher, Fraunhofer Institute of Production Technology (Germany)
Richard Meier, Ludwig-Maximilians-Univ. Munchen (Germany)


Published in SPIE Proceedings Vol. 5143:
Novel Optical Instrumentation for Biomedical Applications
Albert-Claude Boccara, Editor(s)

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