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Proceedings Paper

Optical coherence tomography in clinical examinations of nonpigmented skin malignancies
Author(s): Laura K. Jensen; Lars Thrane; Peter E. Andersen; Andreas Tycho; Finn Pedersen; Stefan Andersson-Engels; Niels Bendsoe; Sune Svanberg; Katarina Svanberg
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Paper Abstract

Optical coherence tomography (OCT) images of basal cell carcinomas (BCCs) have been acquired using a compact handheld proble with an integrated video camera allowing the OCT images to be correlated to a skin surface image. In general the healthy tissue of the skin has an obvious stratified structure, whereas the cancerous tissue shows a more homogeneous structure. Thus it was demonstrated that it is possible to distinguish BCCs from healthy tissue by means of OCT. Furthermore different histological types of BCC were identified. Comparison of OCT images taken prior to and immediately after photodynamic theory clearly shows the tissue response to the treatment, and indicates local oedema in the treated area.

Paper Details

Date Published: 2 October 2003
PDF: 8 pages
Proc. SPIE 5140, Optical Coherence Tomography and Coherence Techniques, (2 October 2003); doi: 10.1117/12.500665
Show Author Affiliations
Laura K. Jensen, Risoe National Lab. (Denmark)
Technical Univ. of Denmark (Denmark)
Lars Thrane, Risoe National Lab. (Denmark)
Peter E. Andersen, Risoe National Lab. (Denmark)
Andreas Tycho, Risoe National Lab. (Denmark)
Finn Pedersen, Risoe National Lab. (Denmark)
Stefan Andersson-Engels, Lund Univ. (Sweden)
Lund Medical Laser Ctr. (Sweden)
Niels Bendsoe, Lund Univ. Hospital (Sweden)
Lund Medical Laser Ctr. (Sweden)
Sune Svanberg, Lund Univ. (Sweden)
Lund Medical Laser Ctr. (Sweden)
Katarina Svanberg, Lund Univ. Hospital (Sweden)
Lund Medical Laser Ctr. (Sweden)

Published in SPIE Proceedings Vol. 5140:
Optical Coherence Tomography and Coherence Techniques
Wolfgang Drexler, Editor(s)

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