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Proceedings Paper

Surface-enhanced Raman scattering of the tear film
Author(s): Janelle M Reyes-Goddard; Anthony C Woodman; Nicholas Stone; Hugh Barr; John Alan Creighton; Yuika Saito; David Batchelder
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Paper Abstract

When human tear film’s constituents are identified, it is diagnostically useful. Surface enhanced Raman scattering (SERS) can quickly measure, the components at their low concentrations. Reproducible spectra were collected from evaporated gold thin film and silver mirror reaction glass substrates. Synthetic tears were measured on optimised substrates as proof of principle. Further analysis was used to discriminate between diseased and normal tears.

Paper Details

Date Published: 8 October 2003
PDF: 11 pages
Proc. SPIE 5141, Diagnostic Optical Spectroscopy in Biomedicine II, (8 October 2003); doi: 10.1117/12.500643
Show Author Affiliations
Janelle M Reyes-Goddard, Cranfield Univ. (United Kingdom)
Gloucestershire Royal Hospital (United Kingdom)
Anthony C Woodman, Cranfield Univ. (United Kingdom)
Gloucestershire Royal Hospital (United Kingdom)
Nicholas Stone, Cranfield Univ. (United Kingdom)
Gloucestershire Royal Hospital (United Kingdom)
Hugh Barr, Cranfield Univ. (United Kingdom)
Gloucestershire Royal Hospital (United Kingdom)
John Alan Creighton, Univ. of Kent (United Kingdom)
Yuika Saito, Univ. of Leeds (United Kingdom)
David Batchelder, Univ. of Leeds (United Kingdom)


Published in SPIE Proceedings Vol. 5141:
Diagnostic Optical Spectroscopy in Biomedicine II
Georges A. Wagnieres, Editor(s)

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