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Proceedings Paper

Optical property measurement of thin superficial tissue by using time-resolved spectroscopy
Author(s): Kenji Tanaka; Yukari Tanikawa; Ryuichiro Araki; Yukio Yamada; Eiji Okada
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Paper Abstract

Recently,non-inv sive diagnostic devices using infrared light have been developed and widely use for clinical applications. To develop these devices, optical properties of biological tissue are necessary. We proposed new optical measurement method. By using time-resolved reflectance spectroscopy and Monte Carlo simulation for the analysis of light propagation in sample, it is considered that this new method is able to measure the optical properties of small biological tissues in vivo. In this study,we investigated the possible optical property measurements of superficial layer using this new method. As the later part of the profile of time-resolved reflectance is influenced by the optical property of the deeper layer, time-gating technique is necessary for the measurement of the optical properties of only the superficial layer in order to use the early profile of the time-resolved reflectance measurement. The function f(t), which is described in the new method, is used for evaluation of the measurement of the superficial layer. We suggest that by using the time-gating technique for the new method and small source-detector spacing, the optical properties of the superficial layer with thickness is more than source-detector spacing, can be obtained.

Paper Details

Date Published: 8 October 2003
PDF: 10 pages
Proc. SPIE 5141, Diagnostic Optical Spectroscopy in Biomedicine II, (8 October 2003); doi: 10.1117/12.500443
Show Author Affiliations
Kenji Tanaka, Keio Univ. (Japan)
Yukari Tanikawa, National Institute of Advanced Industrial Science and Technology (Japan)
Ryuichiro Araki, Saitama Medical School (Japan)
Yukio Yamada, Univ. of Electro-Communications (Japan)
Eiji Okada, Keio Univ. (Japan)

Published in SPIE Proceedings Vol. 5141:
Diagnostic Optical Spectroscopy in Biomedicine II
Georges A. Wagnieres, Editor(s)

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