Share Email Print
cover

Proceedings Paper

Effect of thickness of the superficial tissues on the sensitivity profile for optical imaging
Author(s): Eiji Okada
Format Member Price Non-Member Price
PDF $14.40 $18.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

It is important for near-infrared imaging to estimate the sensitivity of detected signal to the change in absorption of tissue resulting from brain activation and the volume of tissue interrogated for a specific source-detector spacing. In this study, light propagation in adult head models is predicted by Monte Carlo simulation in order to investigate the effect of the thickness of the superficial tissues on the partial optical path length in the brain and on the spatial sensitivity profile. The effect of thickness of skull on the partial optical path length and spatial sensitivity profile is almost the same as that of the scalp. The effect of thickness of cerebrospinal fluid layer on the partial optical path length and spatial sensitivity profile is different from that of the scalp and skull. The partial optical path length mainly depends upon the depth of inner skull surface whilst the spatial sensitivity profile is considerably affected by the thickness of the cerebrospinal fluid layer.

Paper Details

Date Published: 15 October 2003
PDF: 8 pages
Proc. SPIE 5138, Photon Migration and Diffuse-Light Imaging, (15 October 2003); doi: 10.1117/12.500389
Show Author Affiliations
Eiji Okada, Keio Univ. (Japan)


Published in SPIE Proceedings Vol. 5138:
Photon Migration and Diffuse-Light Imaging
David A. Boas, Editor(s)

© SPIE. Terms of Use
Back to Top