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Proceedings Paper

Imaging of cartilage degeneration progression in vivo using ultrahigh-resolution OCT
Author(s): Paul R. Herz; Stephane Bourquin; Pei-lin Hsiung; Tony H. Ko; Karl Schneider; James G. Fujimoto; Samuel Adams; Mark Roberts; Nirlep Patel; Mark Brezinski
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Paper Abstract

Ultrahigh resolution OCT is used to visualize experimentally induced osteoarthritis in a rat knee model. Using a Cr4+:Forsterite laser, ultrahigh image resolutions of 5um are achieved. Progression of osteoarthritic remodeling and cartilage degeneration are quantified. The utility of OCT for the assessment of cartilage integrity is demonstrated.

Paper Details

Date Published: 2 October 2003
PDF: 3 pages
Proc. SPIE 5140, Optical Coherence Tomography and Coherence Techniques, (2 October 2003); doi: 10.1117/12.500326
Show Author Affiliations
Paul R. Herz, Massachusetts Institute of Technology (United States)
Stephane Bourquin, Massachusetts Institute of Technology (United States)
Pei-lin Hsiung, Massachusetts Institute of Technology (United States)
Tony H. Ko, Massachusetts Institute of Technology (United States)
Karl Schneider, Massachusetts Institute of Technology (United States)
James G. Fujimoto, Massachusetts Institute of Technology (United States)
Samuel Adams, Brigham and Women's Hospital (United States)
Harvard Medical School (United States)
Mark Roberts, Brigham and Women's Hospital (United States)
Harvard Medical School (United States)
Nirlep Patel, Brigham and Women's Hospital (United States)
Harvard Medical School (United States)
Mark Brezinski, Brigham and Women's Hospital (United States)
Harvard Medical School (United States)


Published in SPIE Proceedings Vol. 5140:
Optical Coherence Tomography and Coherence Techniques
Wolfgang Drexler, Editor(s)

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