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Proceedings Paper

VLSI multichannel track-and-hold potentiostat
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Paper Abstract

Simultaneous mapping of multiple electrical or chemical properties of neural activity facilitates understanding neurological phenomena and their underlying mechanisms. We present a track-and-hold potentiostat performing simultaneous acquisition of 16 independent channels of current ranging five orders of magnitude in dynamic range over four scales down to hundreds of picoamperes. Sampling rate ranges from DC to 200KHz. The system features programmable current gain control, configurable anti-aliasing log-domain filter, triggered current integration and provides differential output ready for asynchronous external analog-to-digital conversion over a compressed dynamic range. We present system description, circuit implementation and experimental results of real-time neurotransmitter concentration measurements from the 16-channel prototype fabricated in a 1.2 micron CMOS process.

Paper Details

Date Published: 18 April 2003
PDF: 12 pages
Proc. SPIE 5119, Bioengineered and Bioinspired Systems, (18 April 2003); doi: 10.1117/12.499482
Show Author Affiliations
Roman Genov, Univ. of Toronto (Canada)
Milutin Stanacevic, Johns Hopkins Univ. (United States)
Mihir Naware, Johns Hopkins Univ. School of Medicine (United States)
Gert Cauwenberghs, Johns Hopkins Univ. (United States)
Nitish Thakor, Johns Hopkins Univ. School of Medicine (United States)

Published in SPIE Proceedings Vol. 5119:
Bioengineered and Bioinspired Systems
Angel Rodriguez-Vazquez; Derek Abbott; Ricardo Carmona, Editor(s)

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