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Proceedings Paper

Surface microstructuring of biocompatible bone analogue material HAPEX using LIGA technique and embossing
Author(s): Andreas Schneider; Susan Rea; Ejaz Huq; William Bonfield
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Paper Abstract

HAPEX is an artificial bone analogue composite based on hydroxyapatite and polyethylene, which can be applied for growth of bone cells. Due to its biocompatibility and favourable mechanical properties, HAPEX is used for orthopaedic implants like tympanic (middle ear) bones. The morphology of HAPEX surfaces is of high interest and it is believed that surface structuring on a micron scale might improve the growth conditions for bone cells. A new and simple approach for the microstructuring of HAPEX surfaces has been investigated using LIGA technique. LIGA is a combination of several processes, in particular lithography, electroplating and forming/moulding. For HAPEX surface structuring, arrays of dots, grids and lines with typical lateral dimension ranging from 5 μm to 50 μm were created on a chromium photomask and the patterns were transferred into thick SU-8 photoresist (structure height > 10 μm) by UV lithography. Subsequently, the SU-8 structures served as moulds for electroplating nickel on Si wafers and nickel substrates. The final nickel microstructures were used as embossing master for the HAPEX material. Embossing was carried out using a conventional press (> 500 hPa) with the facility to heat the master and the HAPEX. The temperature ranged from ambient to a few degrees above glass transition temperature (Tg) of HAPEX. The paper will include details of the fabrication process and process tolerances in lateral and vertical directions. Data obtained are correlated to the temperature used during embossing.

Paper Details

Date Published: 24 April 2003
PDF: 8 pages
Proc. SPIE 5116, Smart Sensors, Actuators, and MEMS, (24 April 2003); doi: 10.1117/12.498779
Show Author Affiliations
Andreas Schneider, Rutherford Appleton Lab. (United Kingdom)
Susan Rea, Univ. of Cambridge (United Kingdom)
Ejaz Huq, Rutherford Appleton Lab. (United Kingdom)
William Bonfield, Univ. of Cambridge (United Kingdom)

Published in SPIE Proceedings Vol. 5116:
Smart Sensors, Actuators, and MEMS
Jung-Chih Chiao; Vijay K. Varadan; Carles Cané, Editor(s)

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