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Proceedings Paper

Laser-induced macular holes demonstrate impaired choroidal perfusion
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Paper Abstract

Choroidal perfusion was evaluated following the creation of a laser induced macular hole in a nonhuman primate model. Two Rhesus monkeys underwent macular exposures delivered by a Q-switched Nd:YAG laser. The lesions were evaluated with fluorescein angiography and indocyanine green (ICG) angiography . Each lesion produced vitreous hemorrhage and progressed to a full thickness macular hole. ICG angiography revealed no perfusion of the choriocapillaris beneath the lesion centers. Histopathologic evaluation showed replacement of the choriocapillaris with fibroblasts and connective tissue. Nd:YAG, laser-induced macular holes result in long term impairment of choroidal perfusion at the base of the hole due to choroidal scarring and obliteration of the choriocapillaris.

Paper Details

Date Published: 20 June 2003
PDF: 10 pages
Proc. SPIE 4953, Laser and Noncoherent Light Ocular Effects: Epidemiology, Prevention, and Treatment III, (20 June 2003); doi: 10.1117/12.488644
Show Author Affiliations
Jeremiah Brown, Walter Reed Army Institute of Research (United States)
Ophthalmology Associates of San Antonio (United States)
Ronald D. Allen, Brooke Army Medical Ctr. (United States)
Harry Zwick, Walter Reed Army Institute of Research (United States)
Steven T. Schuschereba, Walter Reed Army Institute of Research (United States)
David J. Lund, Walter Reed Army Institute of Research (United States)
Bruce E. Stuck, Walter Reed Army Institute of Research (United States)


Published in SPIE Proceedings Vol. 4953:
Laser and Noncoherent Light Ocular Effects: Epidemiology, Prevention, and Treatment III
Bruce E. Stuck; Michael Belkin, Editor(s)

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