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Proceedings Paper

Clinical optical dose measurement for PDT: invasive and noninvasive techniques
Author(s): Roland Bays; L. Winterhalter; H. Funakubo; Philippe Monnier; Jean-Francois Savary; Georges A. Wagnieres; Daniel Braichotte; Andre Chatelain; Hubert van den Bergh; Lars Othar Svaasand; C. W. Burckhardt
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Paper Abstract

Two methods for clinical optical light dosimetry are developed. In the first method, which is invasive, a fluorescent probe attached to an optical fiber is inserted by means of a thin hypodermic needle and measures light transmitted through the cheek as a function of the penetration depth. In the second noninvasive method, the diffusely reflected light intensity, from a small illuminated spot on the surface of the tissue to be investigated, is measured as a function of the radial distance along the surface. Preliminary results with both methods are presented. Simulations of the second measurements, which allow for a simplified extraction procedure of the relevant optical data from such measurements, are also shown.

Paper Details

Date Published: 1 November 1991
PDF: 12 pages
Proc. SPIE 1525, Future Trends in Biomedical Applications of Lasers, (1 November 1991); doi: 10.1117/12.48223
Show Author Affiliations
Roland Bays, Ecole Polytechnique Federale de Lausanne (Switzerland)
L. Winterhalter, Ecole Polytechnique Federale de Lausanne (Switzerland)
H. Funakubo, Ecole Polytechnique Federale de Lausanne (Switzerland)
Philippe Monnier, CHUV Hospital (Switzerland)
Jean-Francois Savary, CHUV Hospital (Switzerland)
Georges A. Wagnieres, Ecole Polytechnique Federale de Lausanne (Switzerland)
Daniel Braichotte, Ecole Polytechnique Federale de Lausanne (Switzerland)
Andre Chatelain, Ecole Polytechnique Federale de Lausanne (Switzerland)
Hubert van den Bergh, Ecole Polytechnique Federale de Lausanne (Switzerland)
Lars Othar Svaasand, Univ. of Trondheim (Norway)
C. W. Burckhardt, Ecole Polytechnique Federale de Lausanne (Switzerland)


Published in SPIE Proceedings Vol. 1525:
Future Trends in Biomedical Applications of Lasers

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