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Proceedings Paper

Imaging of excimer laser vascular tissue ablation by ultrafast photography
Author(s): Ralf Nyga; Walter Neu; M. Preisack; Karl Konstantin Haase; Karl R. Karsch
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Paper Abstract

Ablation and tissue removal of normal and atherosclerotic arterial tissue by UV excimer-laser radiation were probed by taking photographs with a dye laser as a flash light-source. The ablating pulses were transmitted through a fused silica fiber into a cuvette with the samples exposed to saline solution. The delay time of the probing dye-laser pulse with respect to the ablating excimer-laser pulse was varied in the nanosecond range up to several hundred microseconds. The ablation process and the resulting plume above the tissue surface were recorded with a CCD camera attached to a PC-based image processing system. All samples under investigation were fresh human cadaver aortic and femoral artery specimens which had been shock-frozen for less than 48 hours. The arterial segments showed different types of lipid-rich and calcified plaques. Big cavitation bubbles and small tissue particles emerging from the irradiated area have been recorded.

Paper Details

Date Published: 1 November 1991
PDF: 5 pages
Proc. SPIE 1525, Future Trends in Biomedical Applications of Lasers, (1 November 1991); doi: 10.1117/12.48211
Show Author Affiliations
Ralf Nyga, Laser-Lab. Goettingen e.V. (Germany)
Walter Neu, Laser-Lab. Goettingen e.V. (Germany)
M. Preisack, Eberhard Karls Univ. (Germany)
Karl Konstantin Haase, Eberhard Karls Univ. (Germany)
Karl R. Karsch, Eberhard Karls Univ. (Germany)

Published in SPIE Proceedings Vol. 1525:
Future Trends in Biomedical Applications of Lasers

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