Share Email Print

Proceedings Paper

Method for analysis and display of distribution of emphysema in CT scans
Author(s): William J. Kostis; Simina C. Fluture; David F. Yankelevitz; Claudia I. Henschke
Format Member Price Non-Member Price
PDF $14.40 $18.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

A novel method for the assessment and display of the distribution of emphysema in low-dose helical CT scans has been developed. The automated system segments the lung volume and estimates the degree of emphysema as a function of slice position within the lung. Eighty low-dose (120 kVp, 40 mA) high-resolution (2.5 mm slice thickness) CT scans were randomly selected from our lung cancer screening program. Three emphysema assessments were performed on each scan: the traditional method of averaging the degree of emphysema on four pre-selected CT slices, the total volumetric percentage of emphysema, and a graphical display of emphysema burden as a function of slice position based on a sliding window algorithm. The traditional four-slice estimates showed a high correlation (0.98) with the total volumetric percentages, yet provided limited spatial information. In those cases with a higher overall percentage of emphysema, the distribution within the lung as quantified by the new method was more skewed than that of less severe cases or normals. Analysis and display of the spatial distribution of emphysema allows for assessment of emphysema burden within each lung zone, which may be useful for quantitating the type of emphysema and the progression of disease over time.

Paper Details

Date Published: 15 May 2003
PDF: 8 pages
Proc. SPIE 5032, Medical Imaging 2003: Image Processing, (15 May 2003); doi: 10.1117/12.481415
Show Author Affiliations
William J. Kostis, Cornell Univ. (United States)
Simina C. Fluture, Cornell Univ. (United States)
David F. Yankelevitz, Cornell Univ. (United States)
Claudia I. Henschke, Cornell Univ. (United States)

Published in SPIE Proceedings Vol. 5032:
Medical Imaging 2003: Image Processing
Milan Sonka; J. Michael Fitzpatrick, Editor(s)

© SPIE. Terms of Use
Back to Top