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Proceedings Paper

Vascular MR segmentation: wall and plaque
Author(s): Fuxing Yang; Gerhard Holzapfel; Christian Schulze-Bauer; Rudolf Stollberger; Daniel Thedens; Lizann Bolinger; Alan Stolpen; Milan Sonka
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Paper Abstract

Cardiovascular events frequently result from local rupture of vulnerable atherosclerotic plaque. Non-invasive assessment of plaque vulnerability is needed to allow institution of preventive measures before heart attack or stroke occur. A computerized method for segmentation of arterial wall layers and plaque from high-resolution volumetric MR images is reported. The method uses dynamic programming to detect optimal borders in each MRI frame. The accuracy of the results was tested in 62 T1-weighted MR images from 6 vessel specimens in comparison to borders manually determined by an expert observer. The mean signed border positioning errors for the lumen, internal elastic lamina, and external elastic lamina borders were -0.12±0.14 mm, 0.04±0.12mm, and -0.15±0.13 mm, respectively. The presented wall layer segmentation approach is one of the first steps towards non-invasive assessment of plaque vulnerability in atherosclerotic subjects.

Paper Details

Date Published: 15 May 2003
PDF: 9 pages
Proc. SPIE 5032, Medical Imaging 2003: Image Processing, (15 May 2003); doi: 10.1117/12.481147
Show Author Affiliations
Fuxing Yang, Univ. of Iowa (United States)
Gerhard Holzapfel, Technishe Univ. Graz (Austria)
Christian Schulze-Bauer, Technishe Univ. Graz (Austria)
Rudolf Stollberger, Karl-Franzens-Univ. Graz (Austria)
Daniel Thedens, Univ. of Iowa (United States)
Lizann Bolinger, Univ. of Iowa (United States)
Alan Stolpen, Univ. of Iowa (United States)
Milan Sonka, Univ. of Iowa (United States)


Published in SPIE Proceedings Vol. 5032:
Medical Imaging 2003: Image Processing
Milan Sonka; J. Michael Fitzpatrick, Editor(s)

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