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Proceedings Paper

Computer-aided detection (CAD) of breast cancer on full-field digital and screening film mammograms
Author(s): Xuejun Sun; Wei Qian; Xiaoshan Song; Yuyan Qian; Dansheng Song; Robert A. Clark
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Paper Abstract

Full-field digital mammography (FFDM) as a new breast imaging modality has potential to detect more breast cancers or to detect them at smaller sizes and earlier stages compared with screening film mammography (SFM). However, its performance needs verification, and it would pose new problems for the development of CAD methods for breast cancer detection and diagnosis. Performance evaluation of CAD systems on FFDM and SFM has been conducted in this study, respectively. First, an adaptive CAD system employing a series of advanced modules has been developed on FFDM. Second, a standardization approach has been developed to make the CAD system independent of characteristics of digitizer or imaging modalities for mammography. CAD systems developed previously for SFM and developed in this study for FFDM have been evaluated on FFDM and SFM images without and with standardization, respectively, to examine the performance improvement of the CAD system developed in this study. Computerized free-response receiver operating characteristic (FROC) analysis has been adopted as performance evaluation method. Compared with previous one, the CAD system developed in this study demonstrated significantly performance improvements. However, the comparison results have shown that the performances of final CAD system in this study are not significantly different on FFDM and on SFM after standardization. It needs further study on the assessment of CAD system performance on FFDM and SFM modalities.

Paper Details

Date Published: 15 May 2003
PDF: 10 pages
Proc. SPIE 5032, Medical Imaging 2003: Image Processing, (15 May 2003); doi: 10.1117/12.481125
Show Author Affiliations
Xuejun Sun, Univ. of South Florida (United States)
Wei Qian, Univ. of South Florida (United States)
Xiaoshan Song, Univ. of South Florida (United States)
Yuyan Qian, Univ. of South Florida (United States)
Dansheng Song, Univ. of South Florida (United States)
Robert A. Clark, Univ. of South Florida (United States)


Published in SPIE Proceedings Vol. 5032:
Medical Imaging 2003: Image Processing
Milan Sonka; J. Michael Fitzpatrick, Editor(s)

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