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Proceedings Paper

Benefits of contrast-enhanced multidetector row CT colonography for preoperative staging in colorectal cancer patients
Author(s): Gen Iinuma; Noriyuki Moriyama; Mitso Satake; Kunihisa Miyakawa; Yukio Muramatsu; Ukihide Tateishi; Takayuki Akasu; Yousuke Otake; Takahiro Fujii; Toshiaki Kobayashi
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Paper Abstract

Recently, CT colonography has been recognized as an effective option for evaluating colorectal polyps in the USA. We have applied this technique to preoperative staging of colorectal cancer patients with a contrast-enhanced multi-detector row CT (MDCT). The use of manipulated multi-planar reconstruction (MPR) views in contrast-enhanced MDCT colonography proved advantageous for detecting lymph node metastases. Furthermore, 3-dimensional (3D) endoluminal images with Hansfield-transparency settings allowed vascular views of the colorectal wall for identification of invasive colorectal cancers. Using endoluminal images, increase in flow and pooling of blood related to angiogenesis of invasive cancer could be demonstrated, not only in the lymph nodes but also in the colorectal wall. Both MPR views and 3D endoluminal images can be acquired from the same 3D volumetric data generated by helical scanning in MDCT colonography, and both have great potential as modalities for computer-aided diagnosis (CAD) using blood flow information. Therefore the use of CAD can be expected to improve radiologists' diagnostic performance with regard to colorectal cancer.

Paper Details

Date Published: 2 May 2003
PDF: 7 pages
Proc. SPIE 5031, Medical Imaging 2003: Physiology and Function: Methods, Systems, and Applications, (2 May 2003); doi: 10.1117/12.480399
Show Author Affiliations
Gen Iinuma, National Cancer Ctr. Hospital (Japan)
Noriyuki Moriyama, National Cancer Ctr. Hospital (Japan)
Mitso Satake, National Cancer Ctr. Hospital (Japan)
Kunihisa Miyakawa, National Cancer Ctr. Hospital (Japan)
Yukio Muramatsu, National Cancer Ctr. Hospital (Japan)
Ukihide Tateishi, National Cancer Ctr. Hospital (Japan)
Takayuki Akasu, National Cancer Ctr. Hospital (Japan)
Yousuke Otake, National Cancer Ctr. Hospital (Japan)
Takahiro Fujii, National Cancer Ctr. Hospital (Japan)
Toshiaki Kobayashi, National Cancer Ctr. Hospital (Japan)

Published in SPIE Proceedings Vol. 5031:
Medical Imaging 2003: Physiology and Function: Methods, Systems, and Applications
Anne V. Clough; Amir A. Amini, Editor(s)

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