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Proceedings Paper

Two methods for modeling the propagation of terahertz radiation in a layered structure
Author(s): Gillian Claire Walker; Elizabeth Berry; Stephen W. Smye; Nick N. Zinov'ev; Anthony J. Fitzgerald; Robert E. Miles; J. Martyn Chamberlain; Michael A. Smith
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Paper Abstract

Terahertz (THz) radiation is being studied as an investigative tool for skin conditions. Two approaches for describing the propagation of THz radiation through skin are presented and verified using a layered water-based phantom. The skin was assumed to comprise a series of layers of tissue with differing, frequency dependent, properties; the major interaction was assumed to be between THz radiation and water. Based on these assumptions a thin film matrix model and a Monte Carlo model were developed to simulate this situation. In order to test these models, a simple three layer in-vitro phantom was used. This consisted of two 2 mm layers of TPX, encasing a 180 micrometer layer of a water/propanol-1 mixture. Spectroscopic measurements were made in a pulsed THz system for cells with thirteen different water/propanol-1 concentrations. Comparisons between the results from both models and experimental spectra show good correlation, in each case the model was able to simulate the overall trend of the spectra and more detailed features. This suggests that the models may be adapted to investigate THz irradiation of skin. Modeling modifications would include using layer dimensions that were comparable to the constituent layers of skin and using additional layers to describe the organ more thoroughly.

Paper Details

Date Published: 5 June 2003
PDF: 9 pages
Proc. SPIE 5030, Medical Imaging 2003: Physics of Medical Imaging, (5 June 2003); doi: 10.1117/12.480013
Show Author Affiliations
Gillian Claire Walker, Univ. of Leeds (United Kingdom)
Elizabeth Berry, Univ. of Leeds (United Kingdom)
Stephen W. Smye, Leeds Teaching Hospitals (United Kingdom)
Nick N. Zinov'ev, Univ. of Leeds (United Kingdom)
Anthony J. Fitzgerald, Univ. of Leeds (United Kingdom)
Robert E. Miles, Univ. of Leeds (United Kingdom)
J. Martyn Chamberlain, Univ. of Leeds (United Kingdom)
Michael A. Smith, Univ. of Leeds (United Kingdom)


Published in SPIE Proceedings Vol. 5030:
Medical Imaging 2003: Physics of Medical Imaging
Martin J. Yaffe; Larry E. Antonuk, Editor(s)

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