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Proceedings Paper

Distributed image reconstruction for an in-vivo mouse imaging system
Author(s): Sang Chul Lee; Jae Yong Han; In Kon Chun; Soo Yeol Lee; Min Hyoung Cho
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Paper Abstract

Mice have been widely used in various areas of biomedical research such as drug development and genetic engineering. To investigate drug effect or treatment efficacy in the mouse studies, in-vivo mouse imaging modalities have been recently developed. Among various kinds of imaging modalities, micro-CT is expected to be useful in many biological applications since it provides 3-dimensional high-resolution tomographic images. In this study, we have developed a high-resolution micro-CT system using a microfocus x-ray source and a flat panel detector. The flat panel detector contains a CsI scintillator plate, a 2-dimensional photodiode array, and a 12-bit ADC. The photodiode array consists of 2400 x 2400 pixels of 50μm size. In order to improve computing speed in the micro-CT, we have also developed a distributed parallel processing system using multiple computers. The computation-intensive cone-beam reconstruction process has been divided into multiple tasks in a way that each CPU takes care of similar amount of computations. We have linked four desktop computers with dual AMD Athlon processors by Ethernet and optimized the task allocations among them. The developed parallel processing system has shown to have about eight times faster reconstruction speed. It is expected that the distributed image reconstruction technique can be a low cost solution for the in-vivo mouse imaging system.

Paper Details

Date Published: 5 June 2003
PDF: 8 pages
Proc. SPIE 5030, Medical Imaging 2003: Physics of Medical Imaging, (5 June 2003); doi: 10.1117/12.480006
Show Author Affiliations
Sang Chul Lee, Kyung Hee Univ. (South Korea)
Jae Yong Han, Kyung Hee Univ. (South Korea)
In Kon Chun, Kyung Hee Univ. (South Korea)
Soo Yeol Lee, Kyung Hee Univ. (South Korea)
Min Hyoung Cho, Kyung Hee Univ. (South Korea)


Published in SPIE Proceedings Vol. 5030:
Medical Imaging 2003: Physics of Medical Imaging
Martin J. Yaffe; Larry E. Antonuk, Editor(s)

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