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Proceedings Paper

Measurements of ultrasonic backscattered spectral centroid shift from spine in vivo: methodology and preliminary results
Author(s): Keith A. Wear; Brian S. Garra; Melanie C. Pinet; Steven Felker; Jonathan Mai
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Paper Abstract

We have developed a technique to measure backscattered ultrasound from lumbar vertebrae using a commercial ultrasound scanner. The spectral centroid shift between the spine and reference phantom data is an index of attenuation within the spine. From measurements from 11 vertebrae, we found a correlation coefficient of r = -0.61 between spectral centroid shift and bone mineral density (BMD). This negative correlation is expected as denser, more highly attenuating bone would be expected to produce greater downshifts in spectral centroid. This is the first technique performing quantitative ultrasound measurements on trabecular bone in the spine. This study shows that (1) acquisition of ultrasonic backscatter data from human spine in vivo is feasible, and (2) spectral centroid shift exhibits a moderate negative correlation with BMD in accordance with expectations.

Paper Details

Date Published: 23 May 2003
PDF: 3 pages
Proc. SPIE 5035, Medical Imaging 2003: Ultrasonic Imaging and Signal Processing, (23 May 2003); doi: 10.1117/12.479899
Show Author Affiliations
Keith A. Wear, U.S. Food and Drug Administration (United States)
Brian S. Garra, Univ. of Vermont (United States)
Melanie C. Pinet, Univ. of Vermont (United States)
Steven Felker, Univ. of Vermont (United States)
Jonathan Mai, Univ. of Vermont (United States)

Published in SPIE Proceedings Vol. 5035:
Medical Imaging 2003: Ultrasonic Imaging and Signal Processing
William F. Walker; Michael F. Insana, Editor(s)

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