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Proceedings Paper

Image-based biomimetic modeling and its application in computer-aided tissue engineering
Author(s): Andrew Darling; Binil Starly; Connie Gomez; Zhibin Fang; Wei Sun
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Paper Abstract

High resolution SEM, light microscopy, and non-invasive CT/MRI imaging can produce 3D views of anatomy and generate computational tissue models for many biomedical and tissue engineering applications. Recently, the integration of image processing with computer-aided design (CAD), computer aided manufacturing (CAM), and solid freeform fabrication technology has achieved a remarkable advance in the field of computer-aided tissue engineering (CATE). This paper presents an overview of CATE, including its application in computer-aided tissue modeling, computer-aided tissue informatics, and computer-aided tissue scaffold design and manufacturing. An image-based 3D reconstruction approach, along with a discussion of various enabling reverse engineering techniques for structural representation and CAD based modeling of tissue anatomy will be introduced. An example of biomimetic modeling and design of 3D heterogeneous bony tissue structures under anatomical, biological, and mechanical constraints will also be presented.

Paper Details

Date Published: 27 August 2003
PDF: 12 pages
Proc. SPIE 4961, Laser-Tissue Interaction XIV, (27 August 2003); doi: 10.1117/12.479836
Show Author Affiliations
Andrew Darling, Drexel Univ. (United States)
Binil Starly, Drexel Univ. (United States)
Connie Gomez, Drexel Univ. (United States)
Zhibin Fang, Drexel Univ. (United States)
Wei Sun, Drexel Univ. (United States)

Published in SPIE Proceedings Vol. 4961:
Laser-Tissue Interaction XIV
Donald Dean Duncan; Steven L. Jacques; Sean J. Kirkpatrick; Andres Kriete, Editor(s)

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