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Proceedings Paper

Detecting neoplastic growths in vivo with autofluorescence imaging
Author(s): Tao Wu; T. H. Cheung; K. W. Lo; Jianan Y. Qu
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Paper Abstract

To evaluate the capabilities of a calibrated autofluorescence imaging method for detecting neoplastic lesions, an imaging system that records autofluorescence images calibrated by the cross-polarized reflection images from excitation was instrumented. Cervical tissue was selected as the living tissue material. Sixteen human subjects were examined in vivo with the imaging system before the loop electrosurgical excision procedure (LEEP). It was found that neoplastic lesions can be differentiated from surrounding normal tissue based on the contrast in the calibrated autofluorescence signals, which from neoplastic lesions were generally lower than that from normal cervical tissue.

Paper Details

Date Published: 22 July 2003
PDF: 7 pages
Proc. SPIE 4958, Advanced Biomedical and Clinical Diagnostic Systems, (22 July 2003); doi: 10.1117/12.479804
Show Author Affiliations
Tao Wu, Hong Kong Univ. of Science and Technology (China)
T. H. Cheung, Chinese Univ. of Hong Kong (China)
K. W. Lo, Chinese Univ. of Hong Kong (China)
Jianan Y. Qu, Hong Kong Univ. of Science and Technology (China)


Published in SPIE Proceedings Vol. 4958:
Advanced Biomedical and Clinical Diagnostic Systems
Tuan Vo-Dinh; Warren S. Grundfest; David A. Benaron; Gerald E. Cohn, Editor(s)

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