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Proceedings Paper

Dynamic study of irradiated artificial skin using OCT
Author(s): Woonggyu Jung; Bunsho Kao; Kristen M. Kelly; Zhihua Ding; J. Stuart Nelson; Zhongping Chen
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Paper Abstract

We report a novel application of optical coherence tomography (OCT), to monitor post-laser irradiation collagen injury in skin model. An artificial skin model (RAFT) which closely approximates human skin, was irradiated with a Perovskite laser (λ = 1341 nm). We investigated dynamic changes in a RAFT after laser irradiation through OCT and compared the results to those of histology. OCT images clearly delineated areas of post-irradiation collagen injury and allowed non-invasive monitoring of the wound healing process. Histology was correlated well with OCT images. OCT has advantages because it is non-invasive and allows serial monitoring at the same site over time. Our study showed that OCT may be a useful tool for determination of optimal parameters for non-ablative laser skin rejuvenation (NALSR) using different devices.

Paper Details

Date Published: 8 July 2003
PDF: 7 pages
Proc. SPIE 4956, Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine VII, (8 July 2003); doi: 10.1117/12.479043
Show Author Affiliations
Woonggyu Jung, Beckman Laser Institute/Univ. of California/Irvine (United States)
Bunsho Kao, Beckman Laser Institute/Univ. of California/Irvine (United States)
Kristen M. Kelly, Beckman Laser Institute/Univ. of California/Irvine (United States)
Zhihua Ding, Beckman Laser Institute/Univ. of California/Irvine (United States)
J. Stuart Nelson, Beckman Laser Institute/Univ. of California/Irvine (United States)
Zhongping Chen, Beckman Laser Institute/Univ. of California/Irvine (United States)


Published in SPIE Proceedings Vol. 4956:
Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine VII
Valery V. Tuchin; Joseph A. Izatt; James G. Fujimoto, Editor(s)

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