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Proceedings Paper

Ultrahigh-resolution optical coherence tomography for enhanced visualization of retinal pathology
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Paper Abstract

An ultrahigh resolution ophthalmic optical coherence tomography (OCT) system has been developed. Using a femtosecond Ti:sapphire laser light source, which generates bandwidths of ~150 nm at 800 nm, real-time, cross-sectional imaging of the retina with ~3 μm axial resolution is possible. Ultrahigh resolution OCT images of retinal morphology were obtained in normal subjects and patients with retinal disease. Intraretinal architectural morphology associated with macular diseases such as macular edema, epiretinal membranes, and macular holes can be visualized with unprecedented resolution. Ultrahigh resolution ophthalmic OCT promises to improve the early diagnosis of retinal diseases as well as enable monitoring of disease progression and the efficacy of therapeutic intervention.

Paper Details

Date Published: 8 July 2003
PDF: 4 pages
Proc. SPIE 4956, Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine VII, (8 July 2003); doi: 10.1117/12.479032
Show Author Affiliations
Tony H. Ko, Massachusetts Institute of Technology (United States)
Wolfgang Drexler, Univ. Wien (Austria)
Lelia Adelina Paunescu, Tufts-New England Medical Ctr. (United States)
Tufts Univ. School of Medicine (United States)
Ingmar Hartl, Massachusetts Institute of Technology (United States)
Ravi K. Ghanta, Massachusetts Institute of Technology (United States)
Joel S. Schuman, Tufts-New England Medical Ctr. (United States)
Tufts Univ. School of Medicine (United States)
James G. Fujimoto, Massachusetts Institute of Technology (United States)


Published in SPIE Proceedings Vol. 4956:
Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine VII
Valery V. Tuchin; Joseph A. Izatt; James G. Fujimoto, Editor(s)

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