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Proceedings Paper

Burn depth determination in human skin using polarization-sensitive optical coherence tomography
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Paper Abstract

Accurate evaluation of the depth of injury in burn victims is of considerable practical value to the surgeon, both for initial determination of resuscitation fluid requirements, and in deciding whether excision and closure of the wound is necessary. Currently, burn depth is most accurately evaluated by visual inspection, though decisions concerning treatment may not be possible for a number of days post-injury. As part of our ongoing efforts to provide an objective, quantitative method for burn depth determination, we present here the results of a study using polarization-sensitive optical coherence tomography (PS-OCT) to detect and measure thermally induced changes in collagen birefringence in skin excised from burn patients. We find that PS-OCT is capable of imaging and quantifying significantly reduced birefringence in burned human skin.

Paper Details

Date Published: 8 July 2003
PDF: 8 pages
Proc. SPIE 4956, Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine VII, (8 July 2003); doi: 10.1117/12.478966
Show Author Affiliations
Mark C. Pierce, Wellman Labs. of Photomedicine (United States)
Harvard Medical School (United States)
Massachusetts General Hospital (United States)
Robert L. Sheridan, Shriners Burns Hospital (United States)
Harvard Medical School (United States)
Massachusetts General Hospital (United States)
Boris Hyle Park, Wellman Labs. of Photomedicine (United States)
Harvard Medical School (United States)
Massachusetts General Hospital (United States)
Barry Cense, Wellman Labs. of Photomedicine (United States)
Harvard Medical School (United States)
Massachusetts General Hospital (United States)
Johannes F. de Boer, Wellman Labs. of Photomedicine (United States)
Harvard Medical School (United States)
Massachusetts General Hospital (United States)


Published in SPIE Proceedings Vol. 4956:
Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine VII
Valery V. Tuchin; Joseph A. Izatt; James G. Fujimoto, Editor(s)

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