Share Email Print
cover

Proceedings Paper

C60 nanoparticle quenching used as a biological label
Author(s): Jun Feng; Sally Mack; Guomin Shan; Shirley Gee; Bruce D. Hammock; Ian M. Kennedy
Format Member Price Non-Member Price
PDF $14.40 $18.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

Carbon 60 has been used in a functionalized form in a bioassay for a common herbicide, atrazine. It was found that the C60 is a very effective quencher of fluorescence from a number of common dyes. C60 was conjugated to atrazine for use in an immunoassay in which fluorescence from rhodamine was measured. Quenching of the rhodamine emission provided a detection scheme in this assay that yielded a very good limit of detection. The C60 quenching scheme can be used with a wide variety of fluorescent dyes, permitting the potential use of a range of small, cheap excitation sources.

Paper Details

Date Published: 12 September 2003
PDF: 8 pages
Proc. SPIE 4967, Genetically Engineered and Optical Probes for Biomedical Applications, (12 September 2003); doi: 10.1117/12.478397
Show Author Affiliations
Jun Feng, Univ. of California, Davis (United States)
Sally Mack, Univ. of California, Davis (United States)
Guomin Shan, Univ. of California, Davis (United States)
Shirley Gee, Univ. of California, Davis (United States)
Bruce D. Hammock, Univ. of California, Davis (United States)
Ian M. Kennedy, Univ. of California, Davis (United States)


Published in SPIE Proceedings Vol. 4967:
Genetically Engineered and Optical Probes for Biomedical Applications
Darryl J. Bornhop; Ramesh Raghavachari; Samuel I. Achilefu; Alexander P. Savitsky, Editor(s)

© SPIE. Terms of Use
Back to Top