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Proceedings Paper

A fast reconstruction algorithm for implementation of time-series DC optical tomography
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Paper Abstract

A reconstruction technique that allows for real-time recovery of a time series of images is presented. The reconstruction technique is intended for use in a dynamic DC imaging system, and uses a model-based normalized-preconditioned-transformed system equation that considers light diffusion and is suitable for structures having arbitrary geometry and composition. The algorithm was tested on synthetic 2D media containing dynamic optical contrast features, with the presence of added noise and other uncertainties that commonly are present in experimental data. Post-reconstruction analyses performed on the reconstructed image time series show that the algorithm is capable of correctly locating the inclusions (total of eight) with excellent spatiotemporal accuracy, even in the presence of 32% noise and other uncertainties. In addition, a semi-analytic graphical tool we have identified, that can guide design of suitable measurement geometries and selection of appropriate refinement of the imaging operator, is described.

Paper Details

Date Published: 29 July 2003
PDF: 10 pages
Proc. SPIE 4955, Optical Tomography and Spectroscopy of Tissue V, (29 July 2003); doi: 10.1117/12.478230
Show Author Affiliations
Yaling Pei, NIRx Medical Technologies LLC (United States)
Harry L. Graber, SUNY Downstate Medical Ctr. (United States)
Randall Locke Barbour, SUNY/Downstate Medical Ctr. (United States)


Published in SPIE Proceedings Vol. 4955:
Optical Tomography and Spectroscopy of Tissue V
Britton Chance; Robert R. Alfano; Bruce J. Tromberg; Mamoru Tamura; Eva M. Sevick-Muraca, Editor(s)

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