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Proceedings Paper

Flat fluidics: a new route toward programmable biochips
Author(s): Achim Wixforth; Christoph Gauer; Juergen Scriba; Matthias Wassermeier; Roland Kirchner
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Paper Abstract

The miniaturization of chemical and biological processes has made enormous progress driven mainly by genomics and proteomics. Microfluidics is the core technology to realize miniaturized laboratories with feature sizes on a submillimeter scale. Here, we report on a novel microfluidic technology which allows biochips to be programmed so that different biological assays can be performed with only one chip layout. Interdigital transducers integrated on piezoelectric substrates excite surface acoustic waves (SAW) which drive reagents on the surface of the biochip. The reagents can be placed on any desired spot on the chip’s surface, they can be merged, split and brought to reaction. SAW technology can also be used to efficiently agitate small volumes of liquids accelerating diffusion limited reactions considerably.

Paper Details

Date Published: 17 January 2003
PDF: 8 pages
Proc. SPIE 4982, Microfluidics, BioMEMS, and Medical Microsystems, (17 January 2003); doi: 10.1117/12.478156
Show Author Affiliations
Achim Wixforth, Univ. Augsburg (Germany)
Christoph Gauer, Advalytix AG (Germany)
Juergen Scriba, Advalytix AG (Germany)
Matthias Wassermeier, Advalytix AG (Germany)
Roland Kirchner, Advalytix AG (Germany)

Published in SPIE Proceedings Vol. 4982:
Microfluidics, BioMEMS, and Medical Microsystems
Holger Becker; Peter Woias, Editor(s)

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