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Proceedings Paper

Prototype system of laser transillumination computed tomography for early diagnosis of rheumatoid arthritis
Author(s): Yoshiaki Sasaki; Shinji Tanosaki; Jota Suzuki; Ryota Emori; Hiroki Inage; Tetsuya Yuasa; Michiaki Takagi; Akira Ishikawa; Hiroshi Taniguchi; Balasigamani Devaraj; Takao Akatsuka
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Paper Abstract

So far we have shown, through various preliminary imaging experiments with small-animal ankle’s and human finger’s joints both healthy and joint-diseased, that early diagnosis for joint disease such as rheumatoid arthritis (RA) is feasible using a transillumination laser CT. For a practical purpose, we have recently proposed and developed a transillumination laser CT imaging system using optical fibers based on the optical heterodyne detection method for a clinical use. In the proposed system, motion-artifact free images can be obtained because measurements can be performed with the object fixed. In addition, use of fiber-optics enables portability, and robustness against environmental changes in a room, such as variable temperature, air-flow shifts, and unexpected vibrations. The imaging system has the following sensing properties: spatial resolution of 500 μm, a dynamic range of approximately 120 dB, and a minimum-detectable-optical power of 10-14 W as a result of the excellent properties of the heterodyne detection technique. In the present paper, we describe a prototype laser CT imaging system using optical fibers for early diagnosis of joint disease such as rheumatoid arthritis by demonstrating the first in vivo tomographic image of a volunteer’s index finger joint as well as the fundamental imaging properties.

Paper Details

Date Published: 1 July 2003
PDF: 8 pages
Proc. SPIE 4957, Optical Fibers and Sensors for Medical Applications III, (1 July 2003); doi: 10.1117/12.478067
Show Author Affiliations
Yoshiaki Sasaki, Yamagata Univ. (Japan)
Shinji Tanosaki, Yamagata Univ. (Japan)
Jota Suzuki, Yamagata Univ. (Japan)
Ryota Emori, Yamagata Univ. (Japan)
Hiroki Inage, Yamagata Univ. (United States)
Tetsuya Yuasa, Yamagata Univ. (Japan)
Michiaki Takagi, Yamagata Univ. (Japan)
Akira Ishikawa, Yamagata Univ. (Japan)
Hiroshi Taniguchi, Iwate Univ. (Japan)
Balasigamani Devaraj, New Focus, Inc. (United States)
Takao Akatsuka, Yamagata Univ. (Japan)

Published in SPIE Proceedings Vol. 4957:
Optical Fibers and Sensors for Medical Applications III
Israel Gannot, Editor(s)

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