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Proceedings Paper

Detection of glaucomatous retinal nerve fiber layer damage by scanning laser polarimetry with variable corneal compensation
Author(s): Qienyuan Zhou; Jerry Reed; Ryan W. Betts; Peter Karl Trost; Pak-Wai Lo; Charles Wallace; Richard H. Bienias; Guoqiang Li; Ross Winnick; William A. Papworth; Michael Sinai
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Paper Abstract

One of the earliest signs of glaucoma presence is defects in the retinal nerve fiber layer (RNFL). Scanning laser polarimetry (SLP) provides objective assessment of RNFL, a birefringent tissue, by measuring the total retardation in the reflected light. SLP provides a potential tool for early detection of glaucoma and its progression. The birefringence of the anterior segment of the eye, mainly the cornea, is a confounding variable to SLP's clinical application, if compensation cannot be achieved properly. This paper presents a new SLP system, GDx VCC (Laser Diagnostic Technologies, Inc., San Diego, CA), with a variable corneal compensator (VCC) to achieve individualized corneal compensation. Clinical application of this device in glaucoma detection is also demonstrated.

Paper Details

Date Published: 14 July 2003
PDF: 10 pages
Proc. SPIE 4951, Ophthalmic Technologies XIII, (14 July 2003); doi: 10.1117/12.477975
Show Author Affiliations
Qienyuan Zhou, Laser Diagnostic Technologies, Inc. (United States)
Jerry Reed, Laser Diagnostic Technologies, Inc. (United States)
Ryan W. Betts, Laser Diagnostic Technologies, Inc. (United States)
Peter Karl Trost, Laser Diagnostic Technologies, Inc. (United States)
Pak-Wai Lo, Laser Diagnostic Technologies, Inc. (United States)
Charles Wallace, Laser Diagnostic Technologies, Inc. (United States)
Richard H. Bienias, Laser Diagnostic Technologies, Inc. (United States)
Guoqiang Li, Laser Diagnostic Technologies, Inc. (United States)
Ross Winnick, Laser Diagnostic Technologies, Inc. (United States)
William A. Papworth, Laser Diagnostic Technologies, Inc. (United States)
Michael Sinai, Laser Diagnostic Technologies, Inc. (United States)


Published in SPIE Proceedings Vol. 4951:
Ophthalmic Technologies XIII
Fabrice Manns; Per G. Söderberg; Arthur Ho, Editor(s)

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