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Proceedings Paper

Utilizing Yucatan mini-pigs for 1318-nm skin exposure ED50 determination
Author(s): Golda C. H. Winston; Willie L. Greene; Thomas E. Johnson
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Paper Abstract

Yucatan Mini-pigs were exposed on their flank to 0.5 milli second 1318 nm pulses of laser light. The ED50 damage threshold was determined for this laser exposure combination. The skin was assessed for injury immediately, at 1 hour, 24 hours and three days post exposure. Generally, at least 24 hours was required for visible lesions to form. It was found that as the duration between exposure and assessment expanded the injury was more easily visualized. Tissue samples were collected for histology at one hour, 24 hours and three days. Histologic sections will be presented in future work. It was also found that the topical application of mineral oil to the area of interest was found to greatly increase the ease of identification of injuries.

Paper Details

Date Published: 27 August 2003
PDF: 5 pages
Proc. SPIE 4961, Laser-Tissue Interaction XIV, (27 August 2003); doi: 10.1117/12.477675
Show Author Affiliations
Golda C. H. Winston, Uniformed Services Univ. of the Health Sciences (United States)
Willie L. Greene, Uniformed Services Univ. of the Health Sciences (United States)
Thomas E. Johnson, Uniformed Services Univ. of the Health Sciences (United States)

Published in SPIE Proceedings Vol. 4961:
Laser-Tissue Interaction XIV
Donald Dean Duncan; Steven L. Jacques; Sean J. Kirkpatrick; Andres Kriete, Editor(s)

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