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Proceedings Paper

Study of the pressure effect in near-infrared spectroscopy
Author(s): Xuefeng Cheng; Xiaorong Xu
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Paper Abstract

It has been observed for a long time that the compressive pressure applied on the tissue significantly effects the measurement of Near-Infrared Spectroscopy. The clinical study implies a certain level of correlation between the tissue type and its response to pressure. However, this correlation is not quite understood nor quantified yet, especially in the diffuse optical imaging arena. This paper discusses the development of NIRS tissue spectrometer with real time pressure monitoring and a series of pressure regulated experiments we have conducted on human subjects. By analyzing the pattern of the 2D mapping of tissue hemoglobin concentration and oxygen saturation in response to the temporal profile of the compression force, we are able to explore major factors that influence the pressure regulated measurement

Paper Details

Date Published: 29 July 2003
PDF: 10 pages
Proc. SPIE 4955, Optical Tomography and Spectroscopy of Tissue V, (29 July 2003); doi: 10.1117/12.476783
Show Author Affiliations
Xuefeng Cheng, Photonify Technologies, Inc. (United States)
Xiaorong Xu, Photonify Technologies, Inc. (United States)

Published in SPIE Proceedings Vol. 4955:
Optical Tomography and Spectroscopy of Tissue V
Britton Chance; Robert R. Alfano; Bruce J. Tromberg; Mamoru Tamura; Eva M. Sevick-Muraca, Editor(s)

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