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Proceedings Paper

Practical pathology for engineers: how to do the job right the first time
Author(s): Sharon L. Thomsen
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Paper Abstract

Medical device development requires a phase of instrument testing and performance validation using experimental biologic targets including cells, tissues, organs and individuals in vitro and in vivo. In this development phase, qualitative and quantitative pathologic methods can be very useful to evaluate the mechanisms of detection/effect and to map the extent and severity of device energy/tissue interactions. This paper is a general overview of the philosophical and practical aspects of 1) choosing and preparing effective collaborations with biomedical experts, 2) choosing appropriate biologic target tissues and 3) preparing the tissues to obtain optimal pathologic results.

Paper Details

Date Published: 10 June 2003
PDF: 26 pages
Proc. SPIE 4954, Thermal Treatment of Tissue: Energy Delivery and Assessment II, (10 June 2003); doi: 10.1117/12.476635
Show Author Affiliations
Sharon L. Thomsen, Univ. of Texas/Austin (United States)


Published in SPIE Proceedings Vol. 4954:
Thermal Treatment of Tissue: Energy Delivery and Assessment II
Thomas P. Ryan, Editor(s)

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