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Proceedings Paper

NIR time domain diffuse optical tomography experiments on human forearm
Author(s): Huijuan Zhao; Feng Gao; Yukari Tanikawa; Kazuhiro Homma; Yukio Yamada
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Paper Abstract

To date, the applications of near infrared (NIR) diffusion optical tomography (DOT) are mostly focused on the potential of imaging woman breast, human head hemodynamics and neonatal head. For the neonates, who are suffered from ischaemia or hemorrhages in brain, bedside monitoring of the cerebral perfusion situation, e.g., the blood oxygen saturation and blood volume, is necessary for avoiding permanent injure. NIR DOT is on the promising tools because it is noninvasive, smaller in size, and moveable. Prior to achieving the ultimate goal of imaging infant brain and woman breast using DOT, in this paper, the developed methodologies are justified by imaging in vivo human forearms. The absolute absorption- and scattering-coefficient images revealed the inner structure of the forearm and the bones were clearly distinguished from the muscle. The differential images showed the changes in oxy-hemoglobin, deoxy-hemoglobin and blood volume during the hand-gripping exercises, which are consistent with the physiological process reported on literatures.

Paper Details

Date Published: 29 July 2003
PDF: 10 pages
Proc. SPIE 4955, Optical Tomography and Spectroscopy of Tissue V, (29 July 2003); doi: 10.1117/12.476557
Show Author Affiliations
Huijuan Zhao, National Institute of Advanced Industrial Science and Technology (Japan)
Feng Gao, National Institute of Advanced Industrial Science and Technology (Japan)
Yukari Tanikawa, National Institute of Advanced Industrial Science and Technology (Japan)
Kazuhiro Homma, National Institute of Advanced Industrial Science and Technology (Japan)
Yukio Yamada, Univ. of Electro-Communications (Japan)
National Institute of Advanced Industrial Science and Technology (Japan)


Published in SPIE Proceedings Vol. 4955:
Optical Tomography and Spectroscopy of Tissue V
Britton Chance; Robert R. Alfano; Bruce J. Tromberg; Mamoru Tamura; Eva M. Sevick-Muraca, Editor(s)

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