Share Email Print
cover

Proceedings Paper

Comparative study of the effects of the use of the CO2 laser and of cholorhexidine on the healing of cutaneous wounds infected by Staphylococcus aureus
Author(s): Marcos André Matos de Oliveira; Antonio Luiz Barbosa Pinheiro; Ana Cristina Azevedo Moreira; Luciana Maria Pedreira Ramalho; Aldo Brugnera; Fatima A. A. Zanin; Taciano Levi Costa Lima
Format Member Price Non-Member Price
PDF $14.40 $18.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

The aim of this study was to compare histologic and microbiogically the use of the CO2 Laser and Chlorohexidine Gluconate (0.5% and 2%) on cutaneous wounds infected by Staphylococcus aureus. Wound infection constitutes a risk for the patients and it is usually associated to increase morbidity, mortality and hospital costs. It is accepted that local treatment of these infections is effective. Standardised wounds created on the dorsum of Wistar rats were infected with Staphylococcus aureus and treated as follows: Group 1: control; Group 2: Chlorohexidien Gluconate (0.5%), 1 min, six days; Group 3: Chlorohexidine Gluconate (2%), 1 min, six days; Group 4: CO2 Laser, CW, RSP, 8W, 10s, single application, maintaining surface debris; Group 5: CO2 Laser, CW, RSP, 8W, 10s, single application, removing surface debris. Eight days after wounding material from the surface of the wound was collected for microbiology and the animals were sacrificed and specimens taken for light microscopy. Microbiological examinations showed that on group 2 the bacteria were not found on 50% of the animals. On group 3 83% were germ-free, on group 4 50% and on group 5 66%. Histological examination showed a better result for CO2 laser treated wounds compared to others. It is concluded that the use of a 2% Cholohexidine solution was more effective on decontaminating the wounds. However, wounds treated with the CO2 laer and with the removal of surface debris healed better than the others.

Paper Details

Date Published: 3 July 2003
PDF: 9 pages
Proc. SPIE 4950, Lasers in Dentistry IX, (3 July 2003); doi: 10.1117/12.476441
Show Author Affiliations
Marcos André Matos de Oliveira, Univ. Federal da Bahia (Brazil)
Antonio Luiz Barbosa Pinheiro, Univ. Federal da Bahia (Brazil)
Univ. do Vale do Paraíba (Brazil)
Ana Cristina Azevedo Moreira, Univ. Federal da Bahia (Brazil)
Luciana Maria Pedreira Ramalho, Univ. Federal da Bahia (Brazil)
Univ. do Vale do Paraíba (Brazil)
Aldo Brugnera, Univ. Camilo Castelo Branco (Brazil)
Fatima A. A. Zanin, Univ. Camilo Castelo Branco (Brazil)
Taciano Levi Costa Lima, Univ. Federal da Bahia (Brazil)
Univ. do Vale do Paraíba (Brazil)


Published in SPIE Proceedings Vol. 4950:
Lasers in Dentistry IX
Peter Rechmann; Daniel Fried; Thomas Hennig, Editor(s)

© SPIE. Terms of Use
Back to Top