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Proceedings Paper

Assessment of the influence of the dose and wavelength of LLLT on the repair of cutaneous wounds
Author(s): Tatiana M.T. Vera Mendez; Antonio Luiz Barbosa Pinheiro; Marcos Tadeu Tavares Pacheco; Luciana Maria Pedreira Ramalho; Patricia Maria do Nascimento
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Paper Abstract

The healing time of surgical wounds is of extreme importance and it is usually associated to a post-operative period free of infection and with less pain and inflammation. The aim of the present study was to compare histologically the effect of the GaAlAs (λ830nm, Thera Lase, DMC, Sao Carlos, SP, Brazil, spot size 0.60mm, 35mW) and InGaAlP (λ685nm, Thera Lase, DMS, Sao Carlos, SP, Brazil, spot size 0.60mm, 35mW) isolated or in association with doses of 20 and 50J/cm2 on cutaneous wounds in the dorsum of the Wistar Rat. The animals were divided into seven groups: Group I - Control (non-irradiated), Group II -λ685nm, 20 J/cm2, Group III - λ830nm, 20 J/cm2, Group IV -λ685nm and λ830nm, 20 J/cm2; Group V - λ685nm,50J/cm2), Group VI - λ830nm,50 J/cm2, and Group VII - λ685nm and 830nm, 50 J/cm2. The animals were sacrificed three, five and seven days after surgery. Light microscopic analysis using H&E and Picrosírius stains showed that, at the end of the experimental period, irradiated subjects showed increased collagen production and organization when compared to non-irradiated controls. Inflammation was still present on all groups at this time. Groups IV (l830nm and λ685nm,20J/cm2) presented better results at the end of the experimental period. It is concluded that LLLT had a positive biomodulatory effect end the repair of cutaneuos wounds.

Paper Details

Date Published: 3 July 2003
PDF: 7 pages
Proc. SPIE 4950, Lasers in Dentistry IX, (3 July 2003); doi: 10.1117/12.476431
Show Author Affiliations
Tatiana M.T. Vera Mendez, Univ. do Vale do Paraiba (Brazil)
Antonio Luiz Barbosa Pinheiro, Univ. do Vale do Paraiba (Brazil)
Univ. Federal da Bahia (Brazil)
Marcos Tadeu Tavares Pacheco, Univ. do Vale do Paraiba (Brazil)
Luciana Maria Pedreira Ramalho, Univ. Federal da Bahia (Brazil)
Patricia Maria do Nascimento, Univ. do Vale do Paraiba (Brazil)

Published in SPIE Proceedings Vol. 4950:
Lasers in Dentistry IX
Peter Rechmann; Daniel Fried; Thomas Hennig, Editor(s)

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