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Proceedings Paper

Shrinkage of polyurethane molecular stamp fixed on epoxy resin modified glass substrate
Author(s): Zhengchun Liu; Quanguo He; Pengfeng Xiao; Jianxin Tang; Nongyue He; Zuhong Lu
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Paper Abstract

The shrinkage of polyurethane stamps used for the in situ synthesis of DNA microarrays via molecular stamping method was studied with Micron XYZ Scope. It was found that the polyurethane stamp fixed on the epoxy resin modified glass strongly and showed minimum linear shrinkage. The linear shrinkage of the whole polyurethane stamp and that of each feature of polyurethane stamp were controlled within 0.0341% and 0.309%, respectively, which were due to the strong van der Waals forces and hydrogen bonds between polyurethane and epoxy resin. It was also confirmed by scanning electron microscope that the polyurethane stamp fixed on the epoxy resin modified glass replicated the patterns of motherboard with a high fidelity. All these underlay the synthesis of DNA microarray through molecular stamping method.

Paper Details

Date Published: 17 January 2003
PDF: 6 pages
Proc. SPIE 4982, Microfluidics, BioMEMS, and Medical Microsystems, (17 January 2003); doi: 10.1117/12.472714
Show Author Affiliations
Zhengchun Liu, Southeast Univ. (China)
Huaihua College (China)
Quanguo He, Southeast Univ. (China)
Pengfeng Xiao, Southeast Univ. (China)
Jianxin Tang, Southeast Univ. (China)
Nongyue He, Southeast Univ. (China)
Zuhong Lu, Southeast Univ. (China)

Published in SPIE Proceedings Vol. 4982:
Microfluidics, BioMEMS, and Medical Microsystems
Holger Becker; Peter Woias, Editor(s)

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