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Proceedings Paper

Langmuir-Blodgett films of immunoglobulin G and direct immunochemical sensing
Author(s): Illarion V. Turko; Irene A. Pikuleva; Igor S. Yurkevich; Vadim L. Chashchin
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Paper Abstract

Langmuir-Blodgett technique is shown to be a suitable method for construction of the functionally-oriented layers of immunoglobulin G (IgG) which bind antigen better than in the case of chemical immobilization of IgG on the same substrate. It is assumed that the fluorescent detection of the conformational changes in the molecule of IgG or in the regular structures of IgG molecules after the interaction with antigen can be used for the development of the new type of immunosensors.

Paper Details

Date Published: 1 September 1991
PDF: 4 pages
Proc. SPIE 1510, Chemical and Medical Sensors, (1 September 1991); doi: 10.1117/12.47123
Show Author Affiliations
Illarion V. Turko, Institute of Bio-Organic Chemistry (Belarus)
Irene A. Pikuleva, Institute of Bio-Organic Chemistry (Belarus)
Igor S. Yurkevich, Institute of Bio-Organic Chemistry (Belarus)
Vadim L. Chashchin, Institute of Bio-Organic Chemistry (Belarus)

Published in SPIE Proceedings Vol. 1510:
Chemical and Medical Sensors
Otto S. Wolfbeis, Editor(s)

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