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Proceedings Paper

Optical imaging device of retinal function
Author(s): Randy H. Kardon M.D.; Young Kwon M.D.; Paul Truitt; Sheila Coyne Nemeth; Dan T'so; Peter Soliz
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Paper Abstract

An optical imaging device of retina function (OID-RF) has been constructed to record changes in reflected 700-nm light from the fundus caused by retinal activation in response to a visual 535-nm stimulus. The resulting images reveal areas of the retina activated by visual stimulation. This device is a modified fundus camera designed to provide a patterned, moving visual stimulus over a 45-degree field of view to the subject in the green wavelength portion of the visual spectrum while simultaneously imaging the fundus in another, longer wavelength range. Data was collected from 3 normal subjects and recorded for 13 seconds at 4 Hz; 3 seconds were recorded during pre-stimulus baseline, 5 seconds during the stimulus, and 5 seconds post-stimulus. This procedure was repeated several times and, after image registration, the images were averaged to improve signal to noise. The change in reflected intensity from the retina due to the stimulus was then calculated by comparison to the pre-stimulus state. Reflected intensity from areas of stimulated retina began to increase steadily within 1 second after stimulus onset and decayed after stimulus offset. These results indicated that a functional optical signal can be recorded from the human eye.

Paper Details

Date Published: 13 June 2002
PDF: 9 pages
Proc. SPIE 4611, Ophthalmic Technologies XII, (13 June 2002); doi: 10.1117/12.470600
Show Author Affiliations
Randy H. Kardon M.D., Veterans Administration and Univ. of Iowa Hospital and Clinics (United States)
Young Kwon M.D., Veterans Administration and Univ. of Iowa Hospital and Clinics (United States)
Paul Truitt, Kestrel Corp. (United States)
Sheila Coyne Nemeth, Kestrel Corp. (United States)
Dan T'so, SUNY Health Science Ctr. (United States)
Peter Soliz, Kestrel Corp. (United States)

Published in SPIE Proceedings Vol. 4611:
Ophthalmic Technologies XII
Fabrice Manns; Per G. Soederberg; Arthur Ho, Editor(s)

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