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Proceedings Paper

Depth-resolved birefringence imaging of the primate retinal nerve fiber layer using polarization-sensitive OCT
Author(s): Nathaniel Joseph Kemp; Jesung Park; Jason D. Marsack; Digant P. Dave; Sapun H. Parekh; Thomas E. Milner; Henry Grady Rylander
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Paper Abstract

Imaging the optical phase retardation per unit depth (OPR/UD) in the retinal nerve fiber layer (RNFL) may aid in glaucoma diagnosis. Polarization Sensitive Optical Coherence Tomography (PSOCT) was used to record in vivo high-resolution images of the RNFL in two cynomologous monkeys. The depth variation in the Stokes vector of reflected light was used to calculate the OPR/UD as a function of RNFL position. OPR/UD decreased from 35 degree(s)/100 micrometers near the optic nerve to 5 degree(s)/100 micrometers at a location 600 micrometers superior to the optic nerve. Variation of OPR/UD in the RNFL with retinal position demonstrates a change in birefringence for different densities of ganglion cell axons. PSOCT may be useful for noninvasive determination of RNFL thickness and fiber density.

Paper Details

Date Published: 13 June 2002
PDF: 7 pages
Proc. SPIE 4611, Ophthalmic Technologies XII, (13 June 2002); doi: 10.1117/12.470599
Show Author Affiliations
Nathaniel Joseph Kemp, Univ. of Texas/Austin (United States)
Jesung Park, Univ. of Texas/Austin (United States)
Jason D. Marsack, Univ. of Texas/Austin (United States)
Digant P. Dave, Univ. of Texas/Austin (United States)
Sapun H. Parekh, Univ. of Texas/Austin (United States)
Thomas E. Milner, Univ. of Texas/Austin (United States)
Henry Grady Rylander, Univ. of Texas/Austin (United States)


Published in SPIE Proceedings Vol. 4611:
Ophthalmic Technologies XII
Fabrice Manns; Per G. Soederberg; Arthur Ho, Editor(s)

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