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Proceedings Paper

Real-time in-situ determination of free Cu(II) at picomolar levels in sea water using a fluorescence lifetime-based fiber optic biosensor
Author(s): Richard B. Thompson; Hui-Hui Zeng; Carol A. Fierke; Gary Fones; James W. Moffett
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Paper Abstract

A continuing issue in chemical oceanography and environmental monitoring is the need for frequent and continuous monitoring of analytes in complex matrices such as sea water and ground waters. Particularly for analytes at trace levels such as Cu(II) in sea water, sampling and analysis of discrete specimens is costly, slow, labor intensive, employs ship time inefficiently, and risks error by contamination. We have developed a fluorescence lifetime- based fiber optic biosensor which demonstrates real time determination of free Cu(II) in coastal waters, in situ, with a subpicomolar detection limit.

Paper Details

Date Published: 4 June 2002
PDF: 7 pages
Proc. SPIE 4625, Clinical Diagnostic Systems: Technologies and Instrumentation, (4 June 2002); doi: 10.1117/12.469783
Show Author Affiliations
Richard B. Thompson, Univ. of Maryland School of Medicine/Baltimore (United States)
Hui-Hui Zeng, Univ. of Maryland School of Medicine/Baltimore (United States)
Carol A. Fierke, Univ. of Michigan (United States)
Gary Fones, Woods Hole Oceanographic Institute (United States)
James W. Moffett, Woods Hole Oceanographic Institute (United States)


Published in SPIE Proceedings Vol. 4625:
Clinical Diagnostic Systems: Technologies and Instrumentation
Gerald E. Cohn, Editor(s)

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